Program | EDRC 2025 Alicante

Program

THURSDAY, SEPTEMBER 25th
08:00 – 10:00	EDB MEETING
10:00 - 11:45 Sala Sinfónica	WORKSHOP: A TOUCH OF CELL DEATH AND THE UNEXPECTED NON-LETHAL ROLES OF DEATH-RELATED PROTEINS Organizers: Kim McCall, Hila Toledano, Andreas Bergmann, Eli Arama, Luis Alberto Baena STEP-WISE DESTRUCTION OF NURSE CELLS DURING DEVELOPMENT CELL DEATH IN THE DROSOPHILA OVARY Kim McCall LIPID DROPLETS ACCUMULATE AND DELAY REGULATED CELL DEATH EXECUTION Bertrand Mollereau DECIPHERING MOLECULAR REGULATION OF APOPTOSIS-INDUCED PROLIFERATION Yun Fan CASPASE UBIQUITINATION PROMOTES NF-KB ACTIVATION BY PROTECTION OF THE IKKK COMPLEX Annika Meinander DRONC A TRAFFIC COP ON DUTY WITHIN THE DROSOPHILA NERVOUS SYSTEM Luis Alberto Baena López THE HOMEODOMANI-INTERACTING PROTEIN KINASE HIPK PROMOTES APOPTOSIS BY STABILIZING THE ACTIVE FORM OF DRONC Juan Manuel García Arias TRANSCRIPTION-DEPENDENT AND -INDEPENDENT FUNCTIONS OF DROSOPHILA P53 ISOFORMS IN THE INDUCTION OF APOPTOSIS AND SENESCENE-ASSOCIATED TUMORIGENESIS Carlos Estella
10:00 - 11:45 Sala Cámara	WORKSHOP: THE EXTRACELLULAR MATRIX Organizers: Franck Pichaud, Brian Stramer PATTERNING AN ECM David Bilder INTEGRINS AND MECHANICAL HETEROGENEITY OF THE BASEMENT MEMBRANE INFLUENCE SIMPLE EPITHELIA ARCHITECTURE Lourdes Rincón-Ortega MECHANICAL COUPLING BETWEEN DORSAL AND VENTRAL SURFACES SHAPES THE HALTERE José Carlos Pastor-Pareja SHAPING GROWING TISSUES BY BASEMENT MEMBRANE MECHANICS Stefan Harmansa BASEMENT MEMBRANE PATTERNING GUIDES CELL SHAPE REMODELLING IN THE DEVELOPING DROSOPHILA RETINA Rhian Walther BASEMENT MEMBRANE CONTRIBUTES TO GROWTH CONTROL IN DROSOPHILA WING IMAGINAL DISCS Christian Dahmann GENERATION OF NEW TOOLS TO STUDY BASEMENT MEMBRANE STABILITY DURING DEVELOPMENT Besaiz J. Sánchez-Sánchez
10:00 - 11:45 Sala Conferencias	WORKSHOP: EPITRANSCRIPTOMICS Organizers: Jean-Yves Roignant, Matthias Soller THE NUCLEAR M⁶A PATHWAY REGULATES A COGNITIVE BRAIN FUNCTION VIA NEURONAL CIRCUIT HOMEOSTASIS Eric Lai METTL3 MEDICATED M6A-MODIFICATION IS REQUIRED FOR THE DEVELOPMENT AND FUNCTION OF INDIRECT FLIGHT MUSCLE IN DROSOPHILA Maria Spletter NUCLEAR YTHDC1 IS THE MAIN M⁶A CYTOPLASMIC READER FOR MATERNAL MRNA DECAY DURING THE MATERNAL-TO-ZYGOTIC TRANSITION Martine Simonelig ATAXIN2: MECHANISMS IN MRNP CONDENSATION Joern Huelsmeier NAT10 GOVERNS DEVELOPMENT VIA RIBOSOME ASSEMBLY AND ISR RATHER THAN MRNA ACETYLATION Dong Yan THE PTCH/SPOUT1 METHYLTRANSFERASE DEPOSITS AN M3U MODIFICATION ON 28 S RRNA FOR NORMAL RIBOSOMAL FUNCTION IN FLIES AND HUMANS Yikang S. Rong LOSS OF 2’-O-METHYLATION AT THE TRNA WOBBLE POSITION DISRUPS AGO2-MEDIATED SILENCING: ARE TRNA FRAGMENTS TO BLAME? Nassim Meziane
12:00 - 14:15 Sala Sinfónica	WORKSHOP: INTERORGAN COMMUNICATION IN THE ERA OF OMICS Organizers: Francesca Di Cara, Ditte Skovaa Andersen REGIONAL DIFFERENCES IN INTESTINAL LIPID HANDLING Irene Miguel Aliaga UNDERSTANDING FEMALE-SPECIFIC PREDISPOSITION TO GENETICALLY INDUCED INTESTINAL TUMORS Renald Delanoue INTESTINAL TISSUE MECHANICS REGULATE ANGIOGENESIS VIA VASCULAR PIEZO Jade A. Phillips LACTATE AND GLYCEROL-3-PHOSPHATE REGULATE DEVELOPMENT PLASTICITY DURING LARVAL GROWTH Madhulika Rai SEX DIFFERENCES IN NEUROPEPTIDE-PRODUCING CELLS REGULATE THE MALE-FEMAILE DIFFERENCE IN BODY FAT Elizabeth Readout PROTEOMIC MAPPING OF ORGAN SECRETOMES USING IN VIVO PROXIMITY LABELING Justin Bosch ADIPOCYTE-DERIVED AMINO ACID STORAGE PROTEINS ARE REQUIRED FOR GERMLINE STEM CELL MAINTENANCE IN DROSOPHILA FEMALES Lesley Weaver GUT-BODY CROSSTALK VIA PROTEIN-RESPONSIVE HORMONE TACHYKININ REGULATES FOOD CHOICE AND LIFESPAN Kim Rewitz
12:00 - 14:15 Sala Cámara	WORKSHOP: IT’S ALL ABOUT MITOCHONDRIA Organizers: Tiina S. Salminen, Laura Vesala, Yuliya Basikhina MITOCHONDRIAL PERTURBATIONS ENHANCE CELL-MEDIATED IMMUNITY Tina S. Salminen MITONUCLEAR INTERACTIONS IN A CHANGING WORLD: ENVIRONMENTAL AND GENETIC DETERMINANTS OF MITOCHONDRIAL FUNCTION AND FITNESS IN DROSOPHILA POPULATIONS Stefano Bettinazzi LIFESPAN RESPONSES TO ANTI-AGING INTERVENTIONS ARE SHAPED INTERACTIVELY BY MTDNA AND NDNA VARIATION Adam Dobson ALTERNATIVE OXIDASE-DRIVEN REPROGRAMMING OF THE LARVAL MITOCHONDRIAL ELECTRON TRANSPORT SYSTEM PROMOTES GROWTH IN DROSOPHILA MELANGASTER Geovana S. Garcia MECHANISMS OF CELL- AND TISSUE-SPECIFIC VULNERABILITY TO MITOCHONDRIAL DISEASE Jelle van den Ameele NEURONAL FATTY ACID OXIDATION FUELS MEMORY AFTER INTENSIVE LEARNING Alice Pavlowsky THE CELLULAR BASIS OF MITOCHONDRIAL STRESS SIGNALLING IN THE BRAIN Joseph M. Bateman PANEL DISCUSSION WITH THE PRESENTERS
12:00 - 14:15 Sala Conferencias	WORKSHOP: GENE EXPRESSION IN THE 3D NUCLEAR SPACE: FROM MICRO-CONDENSATES TO NUCLEAR STRUCTURES AND BEYOND Organizers: Thomas Gregor, Samir Merabet DYNAMIC TRANSCRIPTION HUBS AS INTEGRATORS OF SIGNALING PATHWAY ACTIVITES Sara Bray SPATIO-TEMPORAL CONTROL OF TRANSLATION IN EARLY DROSOPHILA EMBRYOGENESIS Pierre Bensidoun ENHANCER-PROMOTER COMMUNICATION DURING EMBRYOGENESIS Yad Ghavi-Helm SPATIAL CHROMATIN TRACING REVEALS CELL-TYPE-SPECIFIC 3D STRUCTURES IN ADULT FLY NEURONS Marcelo Nollman CHROMATIN REGULATION OF DROSOPHILA EARLY EMBRYOGENESIS Francesco Cardamone THE LINC COMPLEX SUPPRESSES CHROMATIN REPRESSION AND REGULATES THE SPATIAL ORGANIZATION OF CHROMATIN-RNAPII COMPLEXES Talila Volk SHAPING THE NUCLEUS FOR TRANSCRIPTIONAL AND DEVELOPMENTAL ROBUSTNESS Albert Tsai A NUCLEAR PORE-INSULATOR AXIS REORGANIZES THE GENOME FOR OOCYTE SPECIFICATION Prashanth Rangan NUCLEAR MECHANOSTABILITY EMERGES FROM SATELLITE DNA CONDENSATION Francisca Brändle
15:00 – 17:15 Sala Sinfónica	WORKSHOP: GUT Organizers: Allison Bardin, Lucy O’Brien EXPLORING THE EFFECTS OF MUSCLE-GENERATED MECHANICAL CONSTRAINTS ON THE ADULT INTESTINE Allison Bardin MECHANO-OSMOTIC EXTRUSIONS SHRINK THE GUT FOLLOWING FOOD WITHDRAWAL Emile Magny THE ROLE OF NUCLEAR FACTOR NF-Y IN NUTRIENT-MEDICATED TISSUE TURNOVER Tetiana Strutynska A MATERNAL HORMONE GATES A REPRODUCTIVE CHECKPOINT VIA ENTERIC NEURONS Bryon Silva MAKING AN EMBRYONIC MIDGUT-DISSECTING THE ROL OF THE GATA FACTOR SERPENT IN EMT Kyra Campbell INTESTINAL STEM CELLS ARE SPATIO-TEMOPRALLY SPECIFIED BY NOTCH SUPPRESSION AND WNT ACTIVATION Zheng Guo A NOTCH-BHLH CONNECTION IN ADULT INTESTINAL STEM CELLS: EVIDENCE FOR MUTUAL INHIBITION Joaquín de Navascues DAMAGE RECOGNITION BY INTESTINAL STEM CELLS VIA DRAPER-SRC-SHARK-STAT SIGNALLING PROMOTES ADULT DROSOPHILA MIDGUT REGENERATION Martina Legido REGULATION OF MIDGUT REGENERATION BY XRP1 AND THE ISR Bruce Edgar
15:00 – 17:15 Sala Cámara	WORKSHOP: BIOLOGY OF SEX WORKSHOP Organizers: Elisabeth Rideout, Jenny Regan, Bruno Hurdy MULTIMODAL NANOSCOPY OF LIPID METABOLIC CHANGES IN AGING DROSOPHILA Lingyan Shi ENTEROKINES ARE DRIVERS OF SEX-DEPENDENT METABOLIC AND BEHAVIORAL VARIATION Michael Texada SEX-SPECIFIC DEVELOPMENT OF THE GONAD STEM CELL SYSTEMS Mark Van Doren SEX DIFFERENCES FOLLOWING DNA VIRUS INFECTION IN DROSOPILA Ali Somerville THE IMPACT OF SEX ON SOCIAL MODULATION OF DEFENCE BEHAVIOURS Clara Ferreira THE SEX AND REPRODUCTIVE PLASTICITY OF INTESTINAL MUSCLES Alessandro Mineo SEXUAL DIMORPHISM IN DROSOPHILA GUT INFECTION OUTCOMES Marko Rubinic SEX, DRUGS, AND PRECISION TOXICOLOGY – PERVASIVE SEX-SPECIFIC RESPONSES IN CHEMICAL SAFETY TESTING Jason Tennessen
15:00 – 17:15 Sala Conferencias	WORKSHOP: STRESS AND THE BRAIN: IMPACT OF STRESS ON BRAIN HEALTH Organizers: Christa Rhiner, Erik Storkebaum INTEGRATED STRESS RESPONSE ACTIVATION IN CHARCOT-MARIE-TOOTH DISEASE Erik Storkebaum DETERMINANTS OF THE SELECTIVE LOSS OF DOPAMINERGIC NEURONS IN GENETIC AND CHEMICAL RISK FACTORS FOR PARKINSON’S DISEASE Emi Nagoshi IMMUNE ACTIVATION DURING CRITICAL NEURODEVELOPMENTAL PERIODS AS A CAUSATIVE FACTOR IN INHERITED DYSTONIA Simon Lowe STUDYING LOW NAD+ INDUCED NEURODEGENERATION IN DROSOPHILIA Lukas Neurkomm SLEEP DEPRIVATION INPAIRS PATTERNS SEPARATION BY DISRUPTING SK CHANNEL-REGULATED SPARSE CODING IN DROSOPHILA Sha Liu INHIBITING GLIAL PHAGOCYTOSIS PREVENTS NEURONAL LOSS IN TWO DISTINCT DROSOPHILA MODELS OF NEURODEGENERATION Naden Khateb AUTOPHAGY AND RELATED PROCESSES ORCHESTRATE GLIAL RESPONSES TO NERVOUS SYSTEM INJURY Áron Szabó FROM ROS TO REPAIR: GLIA-MEDIATED OXIDATIVE STRESS IN INJURY- INDUCED BRAIN PLASTICITY Christina Rhiner NOVEL CONNECTION BETWEEN NEUROPATHY TARGET ESTERASE, DEFECTIVE LYSOSOMES, FATTY ACIDS, AND INFLAMATION Mariana Tsap
18:00 – 18:10 Sala Sinfónica	WELCOME ADDRESS
18:10 – 18:40 Sala Sinfónica	EVOLUTION OF NEURAL CIRCUITS EMBO Young Investigator Lecture Plenary speaker: Lucía Prieto-Godino, The Crick (UK)
18:40 – 19:10 Sala Sinfónica	TOWARD A PREDICTIVE UNDERSTANDING OF EPITHELIAL CELL DEATH: FROM COLLECTIVE EFFECTS TO SINGLE CELL DECISION Plenary speaker: Romain Levayer, Institut Pasteur (France)
19:10 – 19:40 Sala Sinfónica	CELLULAR, GENETIC AND MOLECULAR MECHANISMS UNDERLYING THE MORPHOGENESIS OF TUBULAR ORGANS Plenary speaker: Marta Llimargas, Institut de Biologia Molecular de Barcelona-CSIC (Spain)
19:40 – 20:30 Exhibitor Hall	WELCOME COCKTAIL

FRIDAY, SEPTEMBER 26th
09:00 – 09:30 Sala Sinfónica	EVOLUTION OF CYTOPLASMIC DETERMINANTS: LESSONS FROM THE DROSOPHILA GERM LINE Plenary speaker: Cassandra Extavour, Hardvard University (USA)
09:30 - 10:00 Sala Sinfónica	SPYING ON NEUROMODULATOR DYNAMICS IN VIVO BY CONSTRUCTING MULTI-COLOR GENETICALLY-ENCODED SENSORS Plenary speaker: Yulong Li, Peking University (China)
10:00 - 10:30 Exhibitor Hall	COFFEE BREAK
10:30 - 13:00 Sala Sinfónica	DISEASE MODELS Chairs: Thomas Vaccari, Mar Ruiz TOWARDS UNDERSTANDING HOW THE BRAIN REWARD SYSTEM MAY PROMOTE RESILIENCE AND HEALTH Mario Aguilar Aragón THE PARKINSON DISEASE-ASSOCIATED PROTEIN DJ-1 PARTICIPATES IN ENERGY METABOLISM BY MODULATING BOTH MITOCHONDRIAL AND AUTOPHAGIC ACTIVITY Marco Bisaglia ELUCIDATING INTER-ORGAN COMMUNICATION BETWEEN EPITHELIAL TUMOR AND DROSOPHILA LARVAL LYMPH GLAND DURING CANCER-INDUCED CACHEXIA Ujjayita Chowdhury A DROSOPHILA MODEL FOR DENT’S DISEASE REVEALS IMPAIRED ER EXPORT OF CUBILIN AS PATHOGENIC MECHANISM Salómon Christer LOSS OF DROSOPHILA PACS DISRUPTS GOLGI ARCHITECTURE AND CAUSES CYTOKINESIS FAILURES AND SEIZURE-LIKE PHENOTYPE Maria Grazia Giansanti THE ROLE OF LAMP1 IN THE NON-CELL AUTONOMOUS REGULATION OF ENDO-LYSOSOMAL ACIDIFICATION Andreas Jenny DROSOPHILA MELANOGASTER AND HUMAN CELL MODELS OF POLYGLUTAMINE-BASED DISORDERS REVEAL MODULATION OF GLUTAMATE METABOLISM AS A TRANSLATIONAL THERAPEUTIC APPROACH Juan Antonio Navarro AGEING EXACERBATES TUMOUR GROWTH AND PROGRESSION IN A DROSOPHILA COLORECTAL CANCER MODEL Nsikan Nsek TUSC3/OSTG, A COMPONENT OF THE OST COMPLEX, MEDIATES ENDOPLASMIC RETICULUM TRIAGE OF SIGNALING GLYCOPROTEINS Thomas Vaccari STORAGE PROTEINS SUSTAIN TUMOR GROWTH AND ORCHESTRATE HOST DEVELOPMENTAL PROGRAMS Luca Valzania
10:30 - 13:00 Sala Cámara	CELL BIOLOGY Chairs: Jordan Raff, Kyra Campbell ASYMMETRIC MICROTUBULE NUCLEATION FROM GOLGI STACKS PROMOTES OPPOSITE MICROTUBULE POLARITY IN AXONS AND DENDRITES Yagoubat-Merah Akila PRONEURAL DYNAMICS AND FATE SELECTION IN EARY DROSOPHILA NEUROGENESIS David Green HOW DO DIFFERENT ASTROCYTE MORPHOLOGIES ARISE? Inês Lago-Baldaia HOW DO CELLS BUILD COMPLICATED NANOMACHINES? Jordan Raff DRP1 REGULATED STEM CELL PRIMING OF DROSOPHILA MELANOGASTER GERMLINE STEM CELLS INVOLVES LIGHT AND DIET CUES INTEGRATED BY CRY Yoshita S. DROSOPHILA CHITINASE-LIKE PROTEINS ACT AS NECROTIC OPSONINS TO ENHANCE THE CLEARANCE OF DAMAGED CELLS DURING WOUND REPAIR David Salvador-García ANIMAL DEVELOPMENT REQUIRES A PROGRAMMED SWITCH IN EXTRACELLULAR MATRIX STABILITY Besaiz Sánchez-Sánchez COORDINATED CYTOSKELETAL DYNAMICS OF MEMBRANE PROTRUSIONS ORCHESTRATE 3D MORPHOGENESIS IN THE DROSOPHILA PUPAL WING Osamu Shimmi NUCLEAR MECHANICS DURING MESODRM INVAGINATION Magali Suzanne OPTO-E-CADHERIN REVEALS DIFFERENT KEY ROLES OF CELL-CELL ADHESIONS DURING COLLECTIVE CELL MIGRATION WITHIN THE TISSUE Xiaobo Wang
10:30 - 13:00 Sala Conferencias	IMMUNITY & SYMBIOSIS Chairs: Mark Hanson, Michele Crozatier FUNCTIONAL CHARACTERIZATION OF WOLBACHIA-MEDIATED CYTOPLASMIC INCOMPATIBILITY IN D. MELANOGASTER Loppin Benjamin UNRAVELLING THE PLASTICITY AND DIVERSITY OF HEMOCYTES IN DROSOPHILA Pierre Cattenoz PEROXISOME-MEDIATED REGULATION OF IMD-AMYLOID FORMATION: CHASING THE BUILDING BLOCK OF INFLAMMATION Francesca di Cara A BACTERIAL MORPHOLOGY CHANGE TRIGGERED BY SENSING N-ACETYL-GLUCOSAMINE DETERMINES THE RESISTANCE OF PSEUDOMONAS AERUGINOSA TO A SPECIFIC SET OF DROSOPHILA ANTIMICROBIAL PEPTIDES IN SYSTEMIC INFECTION Dominique Ferrandon INFECTION-INDUCED ELEVATION OF GUT GLYCOSAMINOGLYCANS FOSTERS MICROBIOTA EXPANSION IN DROSOPHILA MELANOGASTER Igor Iatsenko MOBILIZING LIPOPROTEINS TO SAVE THE HOST: HOW AN INFECTION-INDUCED POLARIZATION OF MACROPHAGES TRIGGERS SYSTEMIC METABOLIC REWIRING VIA IMPL2 PRODUCTION Gabriela Krejcova SEROTONERGIC NEURONS REGULATE THE DROSOPHILA VASCULAR NICHE TO CONTROL IMMUNE STRESS HEMATOPOIESIS Liu Xiaohui TASTE REGULATION OF IMMUNITY Pierre-Yves Musso SEX DIFFERENCES IN DROSOPHILA INTESTINAL METABOLISM CONTRIBUTE TO SEXUALLY DIMORPHIC INFECTION OUTCOME AND ALTER GUT PATHOGEN VIRULENCE Marko Rubinic DROSOPHILA COMPLEMENT-LIKE MCR ACTS AS A WOUND-INDUCED INFLAMMATORY CHEMOATTRACTANT Alessandro Scopelliti
13:00 – 15:00 Exhibitor Hall	LUNCH BREAK
14:00 – 15:00 Sala Conferencias	ELIFE SESSION: EVOLUTION OF PUBLISHING Speaker: Alessio Bolognesi
15:00 – 16:15 Sala Sinfónica	NEURAL DEVELOPMENT, CIRCUITS & BEHAVIOUR Chairs: Nikos Konstantinides, Emi Nagoshi NEUROSECRETORY SIGNATURE OF NON-NEURONAL INKA CELLS IN THE INSECT TRACHEAL SYSTEM: A COMPARATIVE AND FUNCTIONAL INSIGHT Shreejita Chatterjee FER2 BHLH TRANSCRIPTION FACTOR CONTROLS MIGRATION AND TARGETING OF LAWF NEURONS IN THE DROSOPHILA OPTIC LOBE Sergio Córdoba Casado MAINTAINING THE METABOLIC STATE: FUNCTIONAL AND CONNECTOMIC ANALYSIS OF A SENSORY CIRCUIT BRIDGING LARVAL METABOLICS AND BRAIN IN DROSOPHILA MELANOGASTER Damian Demarest RECEPTOR ATTP AT THE C-TERMINUS (REACT): FUNCTIONAL AND SPATIAL CHARACTERISATION OF CHEMOTRANSMISSION RECEPTORS AT THE SUBCELLULAR LEVEL Miranda Dyson MAPPING NEURONAL CIRCUITS UNDERLYING OVIPOSITION SUBSTRATE PREFERENCE SHIFT IN DROSOPHILA SUZUKII Loris Garino
15:00 – 16:15 Sala Cámara	TRANSCRIPTION & CHROMATIN Chairs: Marcelo Nollmann, Anne Marie Martínez EPIGENETIC CROSS-TALK: POLYCOMB PRC2 COMPLEX AND THE PIWI-PIRNA PATHWAY IN TRANSPOSON SILENCING IN DROSOPHILA OVARIES Abdou Akkouche HOX PROTEINS AS MODULATORS OF CELLULAR COMPETENCE FOR FATE REPROGRAMMING Raul González SINGLE-CELL EPIGENETIC LANDSCAPES THROUGH DROSOPHILA EMBRYOGENESIS Mattias Mannervik LARGE-SCALE CHANGES IN THE BINDING OF THE SWI/SNF CHROMATIN REMODELLING COMPLEX ARE ASSOCIATED WITH TUMOUR FORMATION IN A MODEL OF IDH WILD-TYPE GLIOBLASTOMA Jake Newland HETEROGENEITY OF CHROMOSOME-SCALE GENOME LOOPS IN THE DROSOPHILA BRAIN Aleena Patel
15:00 – 16:15 Sala Conferencias	SIGNALLING Chairs: Marc Amoyel, Estee Kurant MULTIPLE SIGNALLING INPUTS INTEGRATE TO REFINE MORPHOGEN GRADIENT FORMATION AND INSTRUCT PRECISE CELL FATE DECISIONS Alicia Donoghue FEEDBACK REGULATION OF RAS SIGNALLING IN TUMOURIGENESIS Shijun Fang DECIPHERING THE ROLE OF RAB18 SMALL GTPASE IN HEDGEHOG SECRETION Tamas Matusek PRIMITIVE SCALING AND DEATH TRAITS Marisa Merino REGULATION OF NUCLEAR TRANSLOCATION OF B-CATENIN UPON WNT-SIGNALING ACTIVATION: MECHANISTIC INSIGHTS INTO A NOVEL MICROTUBULE MEDIATED NUCLEAR TRANSPORT PROCESS Marek Mlodzik
16:15 – 16:45 Exhibitor Hall	COFFEE BREAK
16:45 – 18:00 Sala Sinfónica	NEURAL DEVELOPMENT, CIRCUITS & BEHAVIOUR Chairs: Nikos Konstantinides, Emi Nagoshi DECIPHERING DISTINCT SIGNALING NETWORKS THAT REGULATE DOPAMINE-MEDIATED LEARNED AND INNATE BEHAVIOURS Dana Guhle EVOLUTION OF NEURONAL DIVERSITY IN THE INSECT OPTIC LOBE Nikos Konstantinides NIMA PROMOTES CELL ADHESION AT THE BLOOD BRAIN BARRIER OF DROSOPHILA NERVOUS SYSTEM Sara Monticelli SEGREGATION OF GLUTAMATERGIC AND GABAERGIC NEUROTRANSMITTER RELEASE IN DROSOPHILA MOTOR NEURONS Rebecca Smith MAPPING THE SENSORIMOTOR CONNECTOME UNDERLYING PROTEIN-SPECIFIC APPETITES IN DROSOPHILA MELANOGASTER Ibrahim Tastekin
16:45 – 18:00 Sala Cámara	TRANSCRIPTION & CHROMATIN Chairs: Marcelo Nollmann, Anne Marie Martínez QUANTIFYING THE SPATIAL ORGANISATION OF OPEN CHROMATIN IN SITU DURING EARLY STAGES OF EMBRYOGENESIS Blanca Pijuan-Sala FOXO - A TRANSCRIPTION FACTOR IVOLVED IN THE PRC1 TUMOR SUPPRESOR FUNCTION Ana-Maria Popmihavlova ULTRABITHORAX (UBX) COOPERATES WITH LAMIN-C TO MEDIATE TRANSCRIPTIONAL REPRESSION OF AUTOPHAGY IN SPECIFIC NUCLEAR REGIONS Merabet Samir NOTCH ACTIVITY COORDINATES DYNAMIC MASTERMIND HUBS TO INSTRUCT TRANSCRIPTION Carmen Santa Cruz Mateos THE DENSE REGULATORY LANDSCAPE OF A DEVELOPMENTAL ENHANCER Yunhan Xie
16:45 – 18:00 Sala Conferencias	SIGNALLING Chairs: Marc Amoyel, Estee Kurant LOSS OF CLASS 3 PI3K COMPLEX LEADS TO RETENTION OF WG AT THE APICAL MEMBRANE IN POLARIZED TISSUE Bojana Pavlovic ROLE OF CELL MORPHOLOGY IN SHAPING NOTCH SIGNALLING DYNAMICS DURING EARLY NEUROGENESIS Prachi Richa EXTRACELLULAR MATRIX REMODELLING PROMOTES TGF-Β-MEDIATED REGENERATIVE RESPONSE IN THE DROSOPHILA ADULT BRAIN AFTER INJURY Juan Sánchez NOTCH IS A LIGAND OF DRAPER MEDIATING SPERMATOGONIA CELL DEATH Hila Toledano AUTOPHAGY REGULATES NOTCH LEVELS DURING DROSOPHILA HEMATOPOIESIS Pablo Wappner
18:00 – 20:00 Exhibitor Hall	POSTER SESSION AND WINE & CHEESE

SATURDAY, SEPTEMBER 27th
09:00 – 09:30 Sala Sinfónica	EVOLUTION AND DIVERSIFICATION OF MIMICRY AND MASQUERADE IN BUTTERFLIES Plenary speaker: Wei Zhang, Peking University (China)
09:30 - 10:00 Sala Sinfónica	FROM FLIES TO DRUGS: BEATING THE ODDS Plenary speaker: Rubén Artero, Universidad de Valencia (Spain)
10:00 - 10:30 Exhibitor Hall	COFFEE BREAK
10:30 - 13:00 Sala Sinfónica	PHYSIOLOGY & METABOLISM Chairs: David Owald, Helena Cocheme MAPPING METABOLIC PROGRAMS IN A WHOLE-ANIMAL AT SINGLE-CELL RESOLUTION Rita Cardoso-Figueiredo MICROBIOME INDUCED REPROGRAMING OF NITROGEN METABOLISM COUNTERACTS THE DELETERIOUS EFFECTS OF AMINO ACID IMBALANCED DIETS Silvia F. Henriques A GENETICALLY-ENCODED METHOD FOR IN VIVO TAGGING AND TRACING OF LIPIDS FROM CELL-TO-CELL Victor Girard TIC AND TAC MICROPROTEINS ENCODED BY A BICISTRONIC RNA CONTROL DROSOPHILA REPRODUCTION Jennifer Zanet GUT MICROBE-DERIVED LACTIC ACID OPTIMIZES HOST ENERGY METABOLISM DURING STARVATION Jason William Millington INTERSECTING EXPERIMENTAL EVOLUTION AND CRISPR SCREENS TO IDENTIFY NOVEL INSECTICIDE RESISTANCE LOCI Richard Benton *INSULIN/INSULIN-LIKE GROWTH FACTOR SIGNALING PATHWAY PROMOTES HIGHER FAT STORAGE IN DROSOPHILA* FEMALES Elizabeth Rideout SOMATIC GLYCOLYSIS SUSTAINS GERM CELL SURVIVAL THROUGH SHUTTLING OF LACTATE IN THE DROSOPHILA TESTIS Diego Sainz de la Maza TRACHEAL CELLS ON DIET: HOW TRACHEAL NUTRITION SHAPES THE PHYSIOLOGY AND METABOLISM OF THE FRUIT FLY Sohela Sarkar METABOLIC PLASTICITY OF THE DROSOPHILA NERVOUS SYSTEM UPON COLD EXPOSURE** Nina Surina
10:30 - 13:00 Sala Cámara	MORPHOGENESIS & ORGANOGENESIS Chairs: Daniel Rios, Maria Leptin THE PATH TO (ALMOST) PERFECT SYMMETRY: INVESTIGATING GROWTH DYNAMICS AND MORPHOGENESIS IN DROSOPHILA WINGS Ettore de Giorgio SCALING OF MORPHOGENETIC FLOW EMERGES FROM GENETIC PATTERNING AND TISSUE MECHANICAL PROPERTIES Julien Delpierre DYNAMICS AND MOLECULAR REGULATION OF THREE-DIMENSIONAL PACKING OF EPITHELIA María Gómez-Lamarca BASEMENT MEMBRANE MECHANICS AND TISSUE-EXTRINSIC FORCES DRIVE SQUAMOUS MORPHOGENESIS IN THE GROWING DROSOPHILA WING DISC Stefan Harmansa DROSOPHILA EMBRYONIC NEURAL STROMA ORGANIZATION AND DYNAMICS Katerina Karkali PATTERNED CELL DEATH MODULATES NON-AUTONOMOUSLY WING SHAPE VIA A MECHANICAL FORCE Alexis Matamoro-Vidal COORDINATING CELL FATE SPECIFICATION AND TISSUE REMODELLING IN THE DROSOPHILA EMBRYONIC MIDGUT Andrew Plygawko QUANTIFYING AND MANIPULATING THE MOLECULAR ELASTICITY OF DROSOPHILA MUSCLE Devam Purohit COORDINATION OF DROSOPHILA TRACHEA AND EPIDERMIS DEVELOPMENT BY A SUBSET OF SPECIALIZED ADHESIVE CELLS Daniel Ríos CONTRACTILE-TO-EXPANDING STRESS FIBER SWITCH DURING DROSOPHILA OOGENESIS Ningwei Sun
10:30 - 13:00 Sala Conferencias	STEM CELLS & REGENERATION Chairs: Salvador Herrera, Christa Rhiner A JAK/STAT-PDK1-S6K AXIS BYPASSES SYSTEMIC GROWTH RESTRICTIONS TO PROMOTE REGENERATION Classen Anne-Kathrin SPATIAL WNT SIGNALING FACILITATES MEF2 HETEROGENEITY TO MAINTAIN AN UNDIFFERENTIATED MUSCLE PRECURSOR POOL DURING DEVELOPMENT Josephine Bageritz *TUMOUR-DERIVED ILP8 AND UPD3 CONTROL INTESTINAL PROGENITOR CELLS DEPLETION DURING CACHEXIA IN DROSOPHILA* LARVAE Alexandre Dijane TRITHORAX BALANCES ISC FATE DECISIONS VIA PTX1-MEDIATED REPRESSION OF EE DIFFERENTIATION Virginia Fasoulaki UNRAVELLING THE CIRL/TOLL8 CODE IN ESTABLISHING SPATIAL CELLULAR PATTERNS IN THE DROSOPHILA ADULT MIDGUT EPITHELIUM Alphy John IMMUNE CELLS MEDIATE TRACHEAL RECRUITMENT AND ECM REMODELING TO PRESERVE MUSCLE INTEGRITY AND PROMOTE SURVIVAL Ammar Nourhene LIPID DROPLET ASSOCIATED PROTEINS REGULATE DROSOPHILA BLOOD PROGENITOR FATE AND FUNCTIONAL HETEROGENEITY Yashashwinee Rai A GLIA-DERIVED CYTOKINE REGULATING BRAIN-BODY COMMUNICATION UPON BRAIN INJURY Anabel Rodriguez Simões CALCIUM DYNAMICS AND OVARIAN STEM CELL NICHE AGEING Helena Sánchez-Gómez METABOLIC CROSSTALK BETWEEN THE GUT AND ITS MICROENVIRONMENT SUPPORTS INTESTINAL STEM CELL ADAPTATION DURING TISSUE REGENERATION** Yuanliangzi Tian
13:00 – 14:30 Exhibitor Hall	LUNCH BREAK
13:30 – 14:30 Sala Sinfónica	EUROPEAN DROSOPHILA SOCIETY: GENERAL ASSEMBLY AND FLYBASE INFORMATION SESSION
14:30 – 15:45 Sala Sinfónica	CELL STRESS, GROWTH, PROLIFERATION AND DEATH I Chairs: Gabor Juhasz, Catarina Homem A NOVEL MODEL FOR LIVE-IMAGING TUMOUR CELL DEATH AND REVEALING ITS FUNDAMENTAL ROLE IN TUMOURIGENESIS Andrew Davidson A MOLECULAR SWITCH DOWNSTREAM OF TOLLS FROM INNATE IMMUNITY TO CELL PROLIFERATION IN THE BRAIN Alicia Hidalgo TUMORIGENESIS WITHOUT ONCOGENES: SEQUENTIAL STRESS REWIRES REGENERATION Enrique Martin-Blanco DEVELOPMENTAL DELAY ENSURES GLOBAL TISSUE SIZE ROBUSTNESS UPON LOCAL INDUCTION OF APOPTOSIS Ralitza Staneva MORBIUS, A NEW EF-HAND CALCIUM-BINDING PROTEIN, IS INVOLVED IN CELL COMPETITION Katrin Strobel
14:30 – 15:45 Sala Cámara	METHODS Chairs: Tony Southall, Suzanne Magali A SPLIT DCAS12A PLATFORM FOR EPIGENOME REPROGRAMMING James Johnson *TFTAG – A NOVEL LIBRARY OF ENDOGENOUSLY TAGGED DROSOPHILA* TRANSCRIPTION FACTORS Sebastian Kittelmann MORPHOKIT: A SCALABLE PIPELINE FOR QUANTITATIVE MULTISCALE TISSUE MORPHODYNAMIC Rémi Pigache DIRECT CAPTURE OF CRISPR MUTATIONS AND TRANSCRIPTIONAL CHANGES WITHIN SINGLE CELLS IN VIVO Siamak Redhai A BIOORTHOGONAL METHOD TO TAG AND TRACE BRANCHED-CHAIN AMINO ACIDS AND THEIR METABOLITES** Sebastian Sorge
14:30 – 15:45 Sala Conferencias	RNA BIOLOGY Chairs: Felipe Karam Teixeira, Valérie Hilgers BRIDGING THE GAP BETWEEN DNA AND RNA WITH HOX TRANSCRIPTION FACTORS Julie Carnesecchi NOVEL STOP CODON READTHROUGH STIMULATORY ELEMENTS REVEALED BY HIGH THROUGHPUT SCREENING IN DROSOPHILA CELLS Marco Mariotti ANGEL WING: A CLASS OF ALTERNATIVE SPLICING REGULATORS IN ANIMALS Yikang Rong ELAV MEDIATES CIRCULAR RNA BIOGENESIS IN NEURONS Mengjin Shi RNA ARCHITECTURE AT THE TRANSLATION TERMINATION SITE DETERMINES VENTRAL VEINS LACKING/ DRIFTER (VVL/DFR) READTHROUGH RATES Georg Wolfstetter
15:45 – 16:15 Exhibitor Hall	COFFEE TO GO TO AVAILABLE FOR THE POSTER SESSIONS
15:45 – 17:45 Exhibitor Hall	POSTER SESSION
17:45 – 18:15 Sala Sinfónica	INVERTEBRATE ONCOLOGY: TUMOR-HOST INTERACTIONS IN DROSOPHILA Plenary speaker: David Bilder, University of California-Berkeley (USA)
18:15 – 18:45 Sala Sinfónica	EDS PHD PRIZE FUNCTIONAL-METABOLIC COUPLING IN DISTINCT RENAL CELL TYPES COORDINATES ORGAN-WIDE PHYSIOLOGY Plenary speaker: Jack Holcombe, University of Bristol (UK)
20:30 – 23:55	GALA DINNER Dársena Restaurant Palacio de la Fuente, Muelle Pte., 6, 3033 Alicante

SUNDAY, SEPTEMBER 28th
09:30 – 10:45 Sala Sinfónica	CELL STRESS, GROWTH, PROLIFERATION AND DEATH II Chairs: Gabor Juhasz, Catarina Homem BODY PRESSURE AND CONFINEMENT ENSURE WING GROWTH AND ALLOMETRY DURING PUPAL DEVELOPMENT Dalmiro Blanco Obregón POLYPLOID CELL CYCLE VARIATIONS IN DEVELOPMENT AND CANCER Brian Calvi HBS AND RST ADHESION MOLECULES CONTROL EPITHELIUM ARCHITECTURE VIA A REGIONAL CODE THAT REGULATES CELL ELIMINATION Miquel Alexandre Ferreira Pinto P53-INDUCED SENESCENCE CONTRIBUTES TO TUMORIGENESIS BY PROVOKING A HEIGHTENED RESPONSE TO ECDYSONE Inés Kelleher López TO GROW OR NOT TO GROW – CROSSTALK BETWEEN INTEGRATED STRESS RESPONSE AND MTOR SIGNALING IN REGULATING GROWTH DURING ENTEROBLAST DIFFERENTIATION Terhi Rintakangas
09:30 – 10:45 Sala Cámara	POPULATION GENETICS & EVOLUTION Chairs: Thomas Flatt, Luisa Pallares HOST-DEPENDENT SEX RATIO PLASTICITY IN A SPECIALIST DROSOPHILID Divyansh Mittal DROSOPHILA GLUE AS A NEW MODEL TO UNDERSTAND ADAPTATION AND TO DEVELOP NEW BIOADHESIVES Virginie Courtier-Orgogozo THE EVOLUTION OF MUTATION RATES IN LIGHT OF DEVELOPMENT AND CELL-LINEAGE SELECTION Paco Majic TEMPORAL DYNAMICS OF GENE EXPRESSION DURING METAMORPHOSIS IN TWO DISTANT DROSOPHILA SPECIES Aleksandra Ozerova GENETIC AND ENVIRONMENT-DEPENDENT REGULATION OF TRANSCRIPTIONAL VARIANCE IN OUTBRED DROSOPHILA Luisa Pallares
10:45 - 11:15 Exhibitor Hall	COFFEE BREAK
11:15 - 11:45 Sala Sinfónica	WIRING REGULATORY ELEMENTS TO TARGET GENES David Ish-Horowicz early career group leader lecture Plenary speaker: Maria Gambetta, Université de Lausanne (Switzerland)
11:45 - 12:15 Sala Sinfónica	MECHANISMS OF SELF-CONSUMPTION AND SUPPORT OF TUMOR GROWTH Plenary speaker: Tor Erik Rusten, University of Oslo (Norway)
12:15 – 12:45 Sala Sinfónica	UNDERSTANDING ODOR PROCESSING IN DROSOPHILA: CIRCUITRY, CODING, AND BEHAVIORAL INSIGHTS Plenary speaker: Silke Sachse, Max Planck for Chemical Ecology (Germany)
12:45 – 13:00 Sala Sinfónica	CLOSING REMARKS